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Multiple events on single molecules: Unbiased estimation in single-molecule biophysics
Most analyses of single-molecule experiments consist of binning experimental outcomes into a histogram and finding the parameters that optimize the fit of this histogram to a given data model. Here we show that such an approach can introduce biases in the estimation of the parameters, thus great car...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413656/ https://ncbi.nlm.nih.gov/pubmed/16439482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510509103 |
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