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Multiple events on single molecules: Unbiased estimation in single-molecule biophysics

Most analyses of single-molecule experiments consist of binning experimental outcomes into a histogram and finding the parameters that optimize the fit of this histogram to a given data model. Here we show that such an approach can introduce biases in the estimation of the parameters, thus great car...

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Bibliografski detalji
Glavni autori: Koster, Daniel A., Wiggins, Chris H., Dekker, Nynke H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413656/
https://ncbi.nlm.nih.gov/pubmed/16439482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510509103
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