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Fast dynamics of supercoiled DNA revealed by single-molecule experiments

The dynamics of supercoiled DNA play an important role in various cellular processes such as transcription and replication that involve DNA supercoiling. We present experiments that enhance our understanding of these dynamics by measuring the intrinsic response of single DNA molecules to sudden chan...

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Detalhes bibliográficos
Main Authors: Crut, Aurélien, Koster, Daniel A., Seidel, Ralf, Wiggins, Chris H., Dekker, Nynke H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924543/
https://ncbi.nlm.nih.gov/pubmed/17623785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700333104
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