Expression of gp19K increases the persistence of transgene expression from an adenovirus vector in the mouse lung and liver.

Activation of the cellular immune system and subsequent lysis of vector-transduced cells by adenovirus- or transgene-specific cytotoxic T lymphocytes have been shown to limit transgene expression in animal models. The adenovirus gp19K gene product associates with major histocompatibility complex cla...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Bruder, J T, Jie, T, McVey, D L, Kovesdi, I
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192111/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9311844/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.10.7623-7628.1997
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