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Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

Alteration of the natural tropism of adenovirus (Ad) will permit gene transfer into specific cell types and thereby greatly broaden the scope of target diseases that can be treated by using Ad. We have constructed two Ad vectors which contain modifications to the Ad fiber coat protein that redirect...

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Publicado no:J Virol
Principais autores: Wickham, T J, Tzeng, E, Shears, L L, Roelvink, P W, Li, Y, Lee, G M, Brough, D E, Lizonova, A, Kovesdi, I
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343173/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8221-8229.1997
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