Effect of the E4 region on the persistence of transgene expression from adenovirus vectors.

The utility of adenovirus vectors for gene therapy is limited by the transience of expression that has been observed in various in vivo models. Immunological responses to viral targets can eliminate transduced cells and cause the loss of transgene expression. We previously described the characteriza...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Armentano, D, Zabner, J, Sacks, C, Sookdeo, C C, Smith, M P, St George, J A, Wadsworth, S C, Smith, A E, Gregory, R J
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191351/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032378/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.3.2408-2416.1997
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