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A Chimeric Type 2 Adenovirus Vector with a Type 17 Fiber Enhances Gene Transfer to Human Airway Epithelia

In studies of the genetic disease cystic fibrosis, recombinant adenovirus type 2 (Ad2) and Ad5 are being investigated as vectors to transfer cystic fibrosis transmembrane conductance regulator cDNA to airway epithelia. However, earlier work has shown that human airway epithelia are resistant to infe...

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Detalhes bibliográficos
Main Authors: Zabner, Joseph, Chillon, Miguel, Grunst, Teresa, Moninger, Thomas O., Davidson, Beverly L., Gregory, Richard, Armentano, Donna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112889/
https://ncbi.nlm.nih.gov/pubmed/10482622
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