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A Chimeric Type 2 Adenovirus Vector with a Type 17 Fiber Enhances Gene Transfer to Human Airway Epithelia

In studies of the genetic disease cystic fibrosis, recombinant adenovirus type 2 (Ad2) and Ad5 are being investigated as vectors to transfer cystic fibrosis transmembrane conductance regulator cDNA to airway epithelia. However, earlier work has shown that human airway epithelia are resistant to infe...

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Auteurs principaux: Zabner, Joseph, Chillon, Miguel, Grunst, Teresa, Moninger, Thomas O., Davidson, Beverly L., Gregory, Richard, Armentano, Donna
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112889/
https://ncbi.nlm.nih.gov/pubmed/10482622
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