Wordt geladen...
Discovery of an oncogenic activity in p27(Kip1) that causes stem cell expansion and a multiple tumor phenotype
The cell cycle inhibitor p27(Kip1) also has cyclin–cyclin-dependent kinase (CDK)-independent functions. To investigate the significance of these functions in vivo, we generated a knock-in mouse in which four amino acid substitutions in the cdkn1b gene product prevent its interaction with cyclins and...
Bewaard in:
| Hoofdauteurs: | , , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2007
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1920168/ https://ncbi.nlm.nih.gov/pubmed/17626791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1556607 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|