p27(Kip1) modulates cell migration through the regulation of RhoA activation
The tumor suppressor p27(Kip1) is an inhibitor of cyclin/cyclin-dependent kinase (CDK) complexes and plays a crucial role in cell cycle regulation. However, p27(Kip1) also has cell cycle-independent functions. Indeed, we find that p27(Kip1) regulates cell migration, as p27(Kip1)-null fibroblasts exh...
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| Publicado no: | Genes Dev |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15078817/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1185504 |
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