p27(Kip1) modulates cell migration through the regulation of RhoA activation

The tumor suppressor p27(Kip1) is an inhibitor of cyclin/cyclin-dependent kinase (CDK) complexes and plays a crucial role in cell cycle regulation. However, p27(Kip1) also has cell cycle-independent functions. Indeed, we find that p27(Kip1) regulates cell migration, as p27(Kip1)-null fibroblasts exh...

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Detalles Bibliográficos

Publicado en:	Genes Dev
Principais autores:	Besson, Arnaud, Gurian-West, Mark, Schmidt, Anja, Hall, Alan, Roberts, James M.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Cold Spring Harbor Laboratory Press 2004
Assuntos:	Research Papers
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15078817/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1185504
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