The nef gene products of both simian and human immunodeficiency viruses enhance virus infectivity and are functionally interchangeable.
Adult rhesus macaques infected with nef-defective simian immunodeficiency virus (SIV) exhibit extremely low levels of steady-state virus replication, do not succumb to immunodeficiency disease, and are protected from experimental challenge with pathogenic isolates of SIV. Similarly, rare humans foun...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191513/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094638/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3641-3651.1997 |
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