Repair and evolution of nef in vivo modulates simian immunodeficiency virus virulence.

Experimental evidence from the simian immunodeficiency virus (SIV) model of AIDS has shown that the nef gene is critical in the pathogenesis of AIDS. Consequently, nef is of considerable interest in both antiviral drug and vaccine development. Preliminary findings in two rhesus macaques indicated th...

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Detalhes bibliográficos
Main Authors: Whatmore, A M, Cook, N, Hall, G A, Sharpe, S, Rud, E W, Cranage, M P
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC189330/
https://ncbi.nlm.nih.gov/pubmed/7609080
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