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Repair and evolution of nef in vivo modulates simian immunodeficiency virus virulence.

Experimental evidence from the simian immunodeficiency virus (SIV) model of AIDS has shown that the nef gene is critical in the pathogenesis of AIDS. Consequently, nef is of considerable interest in both antiviral drug and vaccine development. Preliminary findings in two rhesus macaques indicated th...

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書目詳細資料
發表在:J Virol
Principais autores: Whatmore, A M, Cook, N, Hall, G A, Sharpe, S, Rud, E W, Cranage, M P
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 1995
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609080/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.5117-5123.1995
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