The nef gene products of both simian and human immunodeficiency viruses enhance virus infectivity and are functionally interchangeable.

Adult rhesus macaques infected with nef-defective simian immunodeficiency virus (SIV) exhibit extremely low levels of steady-state virus replication, do not succumb to immunodeficiency disease, and are protected from experimental challenge with pathogenic isolates of SIV. Similarly, rare humans foun...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Sinclair, E, Barbosa, P, Feinberg, M B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191513/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094638/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3641-3651.1997
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