Persistence of Pathogenic Challenge Virus in Macaques Protected by Simian Immunodeficiency Virus SIVmacΔnef

Live attenuated simian immunodeficiency virus (SIV) is the most efficient vaccine yet developed in monkey models of human immunodeficiency virus infection. In all successful vaccine trials, attenuation was achieved by inactivating at least the nef gene. We investigated some virological and immunolog...

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Hlavní autoři: Khatissian, Emmanuel, Monceaux, Valérie, Cumont, Marie-Christine, Kieny, Marie-Paule, Aubertin, Anne-Marie, Hurtrel, Bruno
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC114055/
https://ncbi.nlm.nih.gov/pubmed/11152522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1507-1515.2001
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