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Persistence of Pathogenic Challenge Virus in Macaques Protected by Simian Immunodeficiency Virus SIVmacΔnef

Live attenuated simian immunodeficiency virus (SIV) is the most efficient vaccine yet developed in monkey models of human immunodeficiency virus infection. In all successful vaccine trials, attenuation was achieved by inactivating at least the nef gene. We investigated some virological and immunolog...

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Main Authors: Khatissian, Emmanuel, Monceaux, Valérie, Cumont, Marie-Christine, Kieny, Marie-Paule, Aubertin, Anne-Marie, Hurtrel, Bruno
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC114055/
https://ncbi.nlm.nih.gov/pubmed/11152522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1507-1515.2001
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