Persistence of Pathogenic Challenge Virus in Macaques Protected by Simian Immunodeficiency Virus SIVmacΔnef

Live attenuated simian immunodeficiency virus (SIV) is the most efficient vaccine yet developed in monkey models of human immunodeficiency virus infection. In all successful vaccine trials, attenuation was achieved by inactivating at least the nef gene. We investigated some virological and immunolog...

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Detalhes bibliográficos
Main Authors: Khatissian, Emmanuel, Monceaux, Valérie, Cumont, Marie-Christine, Kieny, Marie-Paule, Aubertin, Anne-Marie, Hurtrel, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114055/
https://ncbi.nlm.nih.gov/pubmed/11152522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1507-1515.2001
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