Persistence of Pathogenic Challenge Virus in Macaques Protected by Simian Immunodeficiency Virus SIVmacΔnef

Live attenuated simian immunodeficiency virus (SIV) is the most efficient vaccine yet developed in monkey models of human immunodeficiency virus infection. In all successful vaccine trials, attenuation was achieved by inactivating at least the nef gene. We investigated some virological and immunolog...

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Bibliografiske detaljer
Main Authors: Khatissian, Emmanuel, Monceaux, Valérie, Cumont, Marie-Christine, Kieny, Marie-Paule, Aubertin, Anne-Marie, Hurtrel, Bruno
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114055/
https://ncbi.nlm.nih.gov/pubmed/11152522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1507-1515.2001
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