Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses

ABSTRACT Extracellular vesicles (EVs) or exosomes have been implicated in the pathophysiology of infections and cancer. The negative regulatory factor (Nef) encoded by simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) plays a critical role in the progression to AIDS and impa...

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Detalhes bibliográficos

Principais autores:	Ryan P. McNamara, Lindsey M. Costantini, T. Alix Myers, Blake Schouest, Nicholas J. Maness, Jack D. Griffith, Blossom A. Damania, Andrew G. MacLean, Dirk P. Dittmer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2018-03-01
coleção:	mBio
Assuntos:	HIV Nef SIV exosomes extracellular vesicles microvesicles
Acesso em linha:	https://journals.asm.org/doi/10.1128/mBio.02344-17
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