Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses

ABSTRACT Extracellular vesicles (EVs) or exosomes have been implicated in the pathophysiology of infections and cancer. The negative regulatory factor (Nef) encoded by simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) plays a critical role in the progression to AIDS and impa...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ryan P. McNamara, Lindsey M. Costantini, T. Alix Myers, Blake Schouest, Nicholas J. Maness, Jack D. Griffith, Blossom A. Damania, Andrew G. MacLean, Dirk P. Dittmer
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2018-03-01
Schriftenreihe:	mBio
Schlagworte:	HIV Nef SIV exosomes extracellular vesicles microvesicles
Online-Zugang:	https://journals.asm.org/doi/10.1128/mBio.02344-17
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