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Expression of IL-7 receptor α is necessary but not sufficient for the formation of memory CD8 T cells during viral infection

During many acute viral and bacterial infections, IL-7 receptor α-chain (IL-7Rα) is expressed on a subset of effector CD8 T cells that preferentially develop into long-lived memory CD8 T cells. These cells functionally require IL-7Rα, but it is unclear whether IL-7Rα acts mainly to induce their diff...

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Bibliografiske detaljer
Main Authors: Hand, Timothy W., Morre, Michel, Kaech, Susan M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913873/
https://ncbi.nlm.nih.gov/pubmed/17609371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705007104
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