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Cutting Edge: IL-7-Independent Regulation of IL-7 Receptor α Expression and Memory CD8 T Cell Development

Expression of IL-7Rα on a subset of Ag-specific effector CD8 T cells is believed to identify memory cell precursors. However, whether IL-7 regulates IL-7Rα expression in vivo and is responsible for selective survival of IL-7Rα(+) effector cells is unknown. Our results show that in the absence of IL-...

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Autori principali: Klonowski, Kimberly D., Williams, Kristina J., Marzo, Amanda L., Lefrançois, Leo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847272/
https://ncbi.nlm.nih.gov/pubmed/16982855
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