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Formation of IL-7Rα(hi) and IL-7Rα(lo) CD8 T cells during infection is regulated by the opposing functions of GABPα and Gfi-1
IL-7 is essential for survival of naïve and memory T cells, and IL-7 receptor alpha chain (IL-7Rα) expression is dynamically regulated in activated CD8 T cells during acute viral and bacterial infections. Most virus-specific CD8 T cells become IL-7Rα(lo) and are relatively short-lived, but some esca...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2792750/ https://ncbi.nlm.nih.gov/pubmed/18390712 |
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