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Late CD27 stimulation promotes IL-7Rα transcriptional re-expression and memory T cell qualities in effector CD8(+) T cells

We previously demonstrated that CD27 co-stimulation during a primary CD8+ T cell response was critical for the expression of IL-7Rα on acute effector CD8(+) T cells, providing an essential element in the generation of CD8(+) T cell memory to infectious pathogens. IL-7 plays a critical role in the ge...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Dong, Hang, Buckner, Andrew, Prince, Jessica, Bullock, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824422/
https://ncbi.nlm.nih.gov/pubmed/31199542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.1HI0219-064R
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