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Effects of IL-7 on memory CD8(+) T cell homeostasis are influenced by the timing of therapy in mice
IL-7 is integral to the generation and maintenance of CD8(+) T cell memory, and insufficient IL-7 is believed to limit survival and the persistence of memory CD8(+) T cells. Here, we show that during the mouse T cell response to lymphocytic choriomeningitis virus, IL-7 enhanced the number of memory...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2214844/ https://ncbi.nlm.nih.gov/pubmed/18246202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32020 |
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