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Effects of IL-7 on memory CD8(+) T cell homeostasis are influenced by the timing of therapy in mice

IL-7 is integral to the generation and maintenance of CD8(+) T cell memory, and insufficient IL-7 is believed to limit survival and the persistence of memory CD8(+) T cells. Here, we show that during the mouse T cell response to lymphocytic choriomeningitis virus, IL-7 enhanced the number of memory...

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Autori principali: Nanjappa, Som G., Walent, Jane H., Morre, Michel, Suresh, M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2214844/
https://ncbi.nlm.nih.gov/pubmed/18246202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32020
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