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A novel Met-to-Thr mutation in the YMDD motif of reverse transcriptase from feline immunodeficiency virus confers resistance to oxathiolane nucleosides.

Variants of feline immunodeficiency virus (FIV) that possess a unique methionine-to-threonine mutation within the YMDD motif of reverse transcriptase (RT) were selected by culturing virus in the presence of inhibitory concentrations of (-)-beta-L-2',3'-dideoxy-5-fluoro-3'-thiacytidine...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Smith, R A, Remington, K M, Lloyd, R M, Schinazi, R F, North, T W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC191345/
https://ncbi.nlm.nih.gov/pubmed/9032372
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