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Conformational Dynamics of the αM3 Transmembrane Helix during Acetylcholine Receptor Channel Gating

Muscle acetylcholine receptors are synaptic ion channels that “gate” between closed- and open-channel conformations. We used Φ-value analysis to probe the transition state of the diliganded gating reaction with regard to residues in the M3, membrane-spanning helix of the muscle acetylcholine recepto...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cadugan, David J., Auerbach, Anthony
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913136/
https://ncbi.nlm.nih.gov/pubmed/17513382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.105171
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