Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds.

In vitro assay systems which use recombinant retroviral integrase (IN) and short DNA oligonucleotides fail to recapitulate the full-site integration reaction as it is known to occur in vivo. The relevance of using such circumscribed in vitro assays to define inhibitors of retroviral integration has...

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Εκδόθηκε σε:	J Virol
Κύριοι συγγραφείς:	Hazuda, D, Felock, P, Hastings, J, Pramanik, B, Wolfe, A, Goodarzi, G, Vora, A, Brackmann, K, Grandgenett, D
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 1997
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191122/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.807-811.1997
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