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Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds.

In vitro assay systems which use recombinant retroviral integrase (IN) and short DNA oligonucleotides fail to recapitulate the full-site integration reaction as it is known to occur in vivo. The relevance of using such circumscribed in vitro assays to define inhibitors of retroviral integration has...

Täydet tiedot

Tallennettuna:
Julkaisussa:J Virol
Päätekijät: Hazuda, D, Felock, P, Hastings, J, Pramanik, B, Wolfe, A, Goodarzi, G, Vora, A, Brackmann, K, Grandgenett, D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1997
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191122/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985421/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.807-811.1997
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