Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds.
In vitro assay systems which use recombinant retroviral integrase (IN) and short DNA oligonucleotides fail to recapitulate the full-site integration reaction as it is known to occur in vivo. The relevance of using such circumscribed in vitro assays to define inhibitors of retroviral integration has...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191122/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.807-811.1997 |
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