Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds.

In vitro assay systems which use recombinant retroviral integrase (IN) and short DNA oligonucleotides fail to recapitulate the full-site integration reaction as it is known to occur in vivo. The relevance of using such circumscribed in vitro assays to define inhibitors of retroviral integration has...

Полное описание

Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Hazuda, D, Felock, P, Hastings, J, Pramanik, B, Wolfe, A, Goodarzi, G, Vora, A, Brackmann, K, Grandgenett, D
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1997
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191122/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.807-811.1997
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