Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds.

In vitro assay systems which use recombinant retroviral integrase (IN) and short DNA oligonucleotides fail to recapitulate the full-site integration reaction as it is known to occur in vivo. The relevance of using such circumscribed in vitro assays to define inhibitors of retroviral integration has...

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Detaylı Bibliyografya
Asıl Yazarlar: Hazuda, D, Felock, P, Hastings, J, Pramanik, B, Wolfe, A, Goodarzi, G, Vora, A, Brackmann, K, Grandgenett, D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC191122/
https://ncbi.nlm.nih.gov/pubmed/8985421
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