Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy.
Recombinant adenoviruses with E1 sequences deleted efficiently transfer genes into a wide variety of target cells. Antigen- and nonantigen-specific responses to the therapy lead to toxicity, loss of transgene expression, and difficulties with vector readministration. We have created new cell lines t...
Kaydedildi:
| Yayımlandı: | J Virol |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1996
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8971023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.12.8934-8943.1996 |
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