Biology of E1-Deleted Adenovirus Vectors in Nonhuman Primate Muscle

Adenovirus vectors have been studied as vehicles for gene transfer to skeletal muscle, an attractive target for gene therapies for inherited and acquired diseases. In this setting, immune responses to viral proteins and/or transgene products cause inflammation and lead to loss of transgene expressio...

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Bibliografiske detaljer
Main Authors: Zoltick, Philip W., Chirmule, Narendra, Schnell, Michael A., Gao, Guang-ping, Hughes, Joseph V., Wilson, James M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114928/
https://ncbi.nlm.nih.gov/pubmed/11333904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5222-5229.2001
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