Biology of E1-Deleted Adenovirus Vectors in Nonhuman Primate Muscle

Adenovirus vectors have been studied as vehicles for gene transfer to skeletal muscle, an attractive target for gene therapies for inherited and acquired diseases. In this setting, immune responses to viral proteins and/or transgene products cause inflammation and lead to loss of transgene expressio...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Zoltick, Philip W., Chirmule, Narendra, Schnell, Michael A., Gao, Guang-ping, Hughes, Joseph V., Wilson, James M.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Gene Therapy
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114928/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11333904/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.11.5222-5229.2001
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