In vivo optical imaging of integrin α(V)-β(3 )in mice using multivalent or monovalent cRGD targeting vectors

BACKGROUND: The cRGD peptide is a promising probe for early non-invasive detection of tumors. This study aimed to demonstrate how RAFT-c(-RGDfK-)(4), a molecule allowing a tetrameric presentation of cRGD, improved cRGD-targeting potential using in vivo models of α(V)β(3)-positive or negative tumors....

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Detalhes bibliográficos
Main Authors: Jin, Zhao-Hui, Josserand, Véronique, Foillard, Stéphanie, Boturyn, Didier, Dumy, Pascal, Favrot, Marie-Christine, Coll, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906830/
https://ncbi.nlm.nih.gov/pubmed/17565663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-41
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