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Reduction of renal uptake of (111) In‐DOTA‐labeled and A700‐labeled RAFT‐RGD during integrin α(v)β(3) targeting using single photon emission computed tomography and optical imaging
Integrin α(v)β(3) expression is upregulated during tumor growth and invasion in newly formed endothelial cells in tumor neovasculature and in some tumor cells. A tetrameric RGD‐based peptide, regioselectively addressable functionalized template‐(cyclo‐[RGDfK])4 (RAFT‐RGD), specifically targets integ...
Gespeichert in:
| Veröffentlicht in: | Cancer Sci |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7685062/ https://ncbi.nlm.nih.gov/pubmed/22448775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02286.x |
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