Reduction of renal uptake of (111) In‐DOTA‐labeled and A700‐labeled RAFT‐RGD during integrin α(v)β(3) targeting using single photon emission computed tomography and optical imaging

Integrin α(v)β(3) expression is upregulated during tumor growth and invasion in newly formed endothelial cells in tumor neovasculature and in some tumor cells. A tetrameric RGD‐based peptide, regioselectively addressable functionalized template‐(cyclo‐[RGDfK])4 (RAFT‐RGD), specifically targets integ...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Briat, Arnaud, Wenk, Christiane H. F., Ahmadi, Mitra, Claron, Michael, Boturyn, Didier, Josserand, Véronique, Dumy, Pascal, Fagret, Daniel, Coll, Jean‐Luc, Ghezzi, Catherine, Sancey, Lucie, Vuillez, Jean‐Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2012
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685062/
https://ncbi.nlm.nih.gov/pubmed/22448775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02286.x
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