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Application of click-click chemistry to the synthesis of new multivalent RGD conjugates
New multivalent RGD-containing macromolecules were designed by exploiting two orthogonal chemoselective ligations. They were next applied to a competitive cell adhesion assay and used for the non invasive optical imaging of tumour in small animals.
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| Publicado en: | Org Biomol Chem |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Royal Society of Chemistry
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823385/ https://ncbi.nlm.nih.gov/pubmed/20835451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ob00070a |
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