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Application of click-click chemistry to the synthesis of new multivalent RGD conjugates

New multivalent RGD-containing macromolecules were designed by exploiting two orthogonal chemoselective ligations. They were next applied to a competitive cell adhesion assay and used for the non invasive optical imaging of tumour in small animals.

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Galibert, Mathieu, Sancey, Lucie, Renaudet, Olivier, Coll, Jean-Luc, Dumy, Pascal, Boturyn, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823385/
https://ncbi.nlm.nih.gov/pubmed/20835451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ob00070a
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