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Application of click-click chemistry to the synthesis of new multivalent RGD conjugates
New multivalent RGD-containing macromolecules were designed by exploiting two orthogonal chemoselective ligations. They were next applied to a competitive cell adhesion assay and used for the non invasive optical imaging of tumour in small animals.
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| Udgivet i: | Org Biomol Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823385/ https://ncbi.nlm.nih.gov/pubmed/20835451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ob00070a |
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