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In vivo optical imaging of integrin α(V)-β(3 )in mice using multivalent or monovalent cRGD targeting vectors
BACKGROUND: The cRGD peptide is a promising probe for early non-invasive detection of tumors. This study aimed to demonstrate how RAFT-c(-RGDfK-)(4), a molecule allowing a tetrameric presentation of cRGD, improved cRGD-targeting potential using in vivo models of α(V)β(3)-positive or negative tumors....
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1906830/ https://ncbi.nlm.nih.gov/pubmed/17565663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-41 |
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