Clustering and Internalization of Integrin α(v)β(3) With a Tetrameric RGD-synthetic Peptide

Integrin α(v)β(3) is overexpressed on neoendothelial cells and frequently on tumor cells. We have developed a peptide-like scaffold (regioselectively addressable functionalized template, RAFT), which holds four cyclo(-RGDfK-) (cRGD) motifs and proved that this molecule (called regioselectively addre...

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Détails bibliographiques
Auteurs principaux: Lucie, Sancey, Elisabeth, Garanger, Stéphanie, Foillard, Guy, Schoehn, Amandine, Hurbin, Corinne, Albiges-Rizo, Didier, Boturyn, Catherine, Souchier, Alexeï, Grichine, Pascal, Dumy, Jean-Luc, Coll
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2009
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760123/
https://ncbi.nlm.nih.gov/pubmed/19259068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.29
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