Φορτώνει......
The antithrombotic potential of selective blockade of talin-dependent integrin α(IIb)β(3) (platelet GPIIb–IIIa) activation
In vitro studies indicate that binding of talin to the β(3) integrin cytoplasmic domain (tail) results in integrin α(IIb)β(3) (GPIIb–IIIa) activation. Here we tested the importance of talin binding for integrin activation in vivo and its biological significance by generating mice harboring point mut...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical Investigation
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1906732/ https://ncbi.nlm.nih.gov/pubmed/17627302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31024 |
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