Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor.

To analyze the basis of affinity modulation of integrin function, we studied cloned stable Chinese hamster ovary cell lines expressing recombinant integrins of the beta 3 family (alpha IIb beta 3 and alpha v beta 3). Antigenic and peptide recognition specificities of the recombinant receptors resemb...

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Detalhes bibliográficos
Main Authors: O'Toole, T E, Loftus, J C, Du, X P, Glass, A A, Ruggeri, Z M, Shattil, S J, Plow, E F, Ginsberg, M H
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC362859/
https://ncbi.nlm.nih.gov/pubmed/2100193
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