Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor.

To analyze the basis of affinity modulation of integrin function, we studied cloned stable Chinese hamster ovary cell lines expressing recombinant integrins of the beta 3 family (alpha IIb beta 3 and alpha v beta 3). Antigenic and peptide recognition specificities of the recombinant receptors resemb...

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Veröffentlicht in:	Cell Regul
Hauptverfasser:	O'Toole, T E, Loftus, J C, Du, X P, Glass, A A, Ruggeri, Z M, Shattil, S J, Plow, E F, Ginsberg, M H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Cell Biology 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362859/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2100193/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.1.12.883
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