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Biochemical characterization of the fidelity of poliovirus RNA-dependent RNA polymerase

BACKGROUND: Putative high mutation rates of RNA viruses are believed to mediate undesirable phenomena, such as emergence of drug resistance. However, very little is known about biochemical fidelity rates for viral RNA-dependent RNA polymerases. Using a recently developed in vitro polymerase assay fo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Freistadt, Marion S, Vaccaro, Joseph A, Eberle, Karen E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904441/
https://ncbi.nlm.nih.gov/pubmed/17524144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-44
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