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Biochemical characterization of the fidelity of poliovirus RNA-dependent RNA polymerase
BACKGROUND: Putative high mutation rates of RNA viruses are believed to mediate undesirable phenomena, such as emergence of drug resistance. However, very little is known about biochemical fidelity rates for viral RNA-dependent RNA polymerases. Using a recently developed in vitro polymerase assay fo...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904441/ https://ncbi.nlm.nih.gov/pubmed/17524144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-44 |
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