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Hepcidin regulation: ironing out the details
Hepcidin is a peptide hormone secreted by the liver that plays a central role in the regulation of iron homeostasis. Increased hepcidin levels result in anemia while decreased expression is the causative feature in most primary iron overload diseases. Mutations in hemochromatosis type 2 (HFE2), whic...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904333/ https://ncbi.nlm.nih.gov/pubmed/17607352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32701 |
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