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Hepcidin regulation: ironing out the details

Hepcidin is a peptide hormone secreted by the liver that plays a central role in the regulation of iron homeostasis. Increased hepcidin levels result in anemia while decreased expression is the causative feature in most primary iron overload diseases. Mutations in hemochromatosis type 2 (HFE2), whic...

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Detalhes bibliográficos
Main Authors: De Domenico, Ivana, Ward, Diane M., Kaplan, Jerry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904333/
https://ncbi.nlm.nih.gov/pubmed/17607352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32701
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