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Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
Systemic iron balance is regulated by hepcidin, a peptide hormone secreted by the liver. By decreasing cell surface expression of the iron exporter ferroportin, hepcidin decreases iron absorption from the intestine and iron release from reticuloendothelial stores. Hepcidin excess has been implicated...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904317/ https://ncbi.nlm.nih.gov/pubmed/17607365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31342 |
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