Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

Systemic iron balance is regulated by hepcidin, a peptide hormone secreted by the liver. By decreasing cell surface expression of the iron exporter ferroportin, hepcidin decreases iron absorption from the intestine and iron release from reticuloendothelial stores. Hepcidin excess has been implicated...

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Detaylı Bibliyografya
Asıl Yazarlar: Babitt, Jodie L., Huang, Franklin W., Xia, Yin, Sidis, Yisrael, Andrews, Nancy C., Lin, Herbert Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904317/
https://ncbi.nlm.nih.gov/pubmed/17607365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31342
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