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Constitutively Activated Stat3 Induces Tumorigenesis and Enhances Cell Motility of Prostate Epithelial Cells through Integrin β6

The persistent activation of signal transducer and activator of transcription 3 (Stat3) is a common feature of prostate cancer. However, little is known about the Stat3 targets that may mediate prostate tumorigenesis. The introduction of an activating mutant form of Stat3 (Stat3-C) into immortalized...

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Detalhes bibliográficos
Main Authors: Azare, Janeen, Leslie, Kenneth, Al-Ahmadie, Hikmat, Gerald, William, Weinreb, Paul H., Violette, Shelia M., Bromberg, Jacqueline
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900039/
https://ncbi.nlm.nih.gov/pubmed/17438134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02404-06
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