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Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C
Persistently activated Stat3 is found in many different cancers, including ≈60% of breast tumors. Here, we demonstrate that a constitutively activated Stat3 transforms immortalized human mammary epithelial cells and that this oncogenic event requires the activity of matrix metalloproteinase-9 (MMP-9...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC489981/ https://ncbi.nlm.nih.gov/pubmed/15249664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404100101 |
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