Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer

INTRODUCTION: Signal transducer and activator of transcription 3 (Stat3) is constitutively tyrosine-phosphorylated in approximately 50% of primary breast carcinomas. A number of different mechanisms responsible for Stat3 activation, including abnormal activation of receptor tyrosine kinases, Src, an...

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Detalhes bibliográficos
Main Authors: Berishaj, Marjan, Gao, Sizhi Paul, Ahmed, Simi, Leslie, Kenneth, Al-Ahmadie, Hikmat, Gerald, William L, Bornmann, William, Bromberg, Jacqueline F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1929096/
https://ncbi.nlm.nih.gov/pubmed/17531096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1680
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