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Cholinergic Anti-Inflammatory Pathway Activity and High Mobility Group Box-1 (HMGB1) Serum Levels in Patients with Rheumatoid Arthritis

High Mobility Group Box-1 (HMGB1) is a cytokine implicated in the pathogenesis of rheumatoid arthritis (RA) and other inflammatory diseases. The cholinergic anti-inflammatory pathway, a vagus nerve-dependent mechanism, inhibits HMGB1 release in experimental disease models. Here, we examine the relat...

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Autores principales: Goldstein, Richard S, Bruchfeld, Annette, Yang, Lihong, Qureshi, Abdul R, Gallowitsch-Puerta, Margot, Patel, Nirav B, Huston, Brett J, Chavan, Sangeeta, Rosas-Ballina, Mauricio, Gregersen, Peter K, Czura, Christopher J, Sloan, Richard P, Sama, Andrew E, Tracey, Kevin J
Formato: Artigo
Lenguaje:Inglês
Publicado: ScholarOne 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899837/
https://ncbi.nlm.nih.gov/pubmed/17597834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2006-00108.Goldstein
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