IL-13 and Epidermal Growth Factor Receptor Have Critical but Distinct Roles in Epithelial Cell Mucin Production

Overproduction of mucus is a central feature of asthma. The cytokine, IL-13, epidermal growth factor receptor (EGFR), and transcription factor, FOXA2, have each been implicated in mucus production, but the mechanistic relationships between these molecules are not yet well understood. To address this...

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Detalhes bibliográficos
Main Authors: Zhen, Guohua, Park, Sung Woo, Nguyenvu, Louis T., Rodriguez, Madeleine W., Barbeau, Rebecca, Paquet, Agnes C., Erle, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899314/
https://ncbi.nlm.nih.gov/pubmed/16980555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0180OC
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